Chemical Data :

IUPAC: (±)-1-(1,3-benzodioxol-5-yl)-2-(methylamino)pentan-1-one

CAS: 698963-77-8

ChemSpider: 29786041

Molecular Weight: 235.278

Molecular Formula: C13H17NO3

Pentylone is a stimulant dug compound of the substituted cathinone class.

Pentylone goes by a number of different names. It has been called Keto-Methylbenzodioxolylpentanamine, βk-Methyl-K, methylenedioxypentedrone and βk-MBDP. It has the systematic and formal IUPAC name (±)-1-(1,3-benzodioxol-5-yl)-2-(methylamino)pentan-1-one.

The chemical has a molar mass of 235.278 grams and empirical formula C13H17NO3.

The substituted cathinones are a series of chemicals that derive their structure from the chemical cathinone. Cathinone is the beta keto analogue of amphetamine. It is found naturally in leaf of the plant Catha edulis which is native to the Horn of Africa and the Arabian Peninsula.

The fresh leaves of this plant have been harvested for over two hundred years and chewed to release the psychoactive alkaloids. This drug preparation is known as Khat, and amongst the alkaloids released, cathinone is the most powerful. Khat is a mild stimulant and social lubricant which farm labourers and manual workers will chew after work to facilitate talk and to reduce tiredness. In contrast, the substituted cathinones such as pentylone are much more powerful stimulants.

They are generally presented in pure powdered form and ingested or insufflated to produce a stimulating “high” in users. For many, they are an alternative to more conventional recreational drugs such as MDMA, speed and cocaine.

The chemical was first developed in the 1960s and patented in 1969. More recently pentylone has surfaced as a “designer drug” and part of the wave of substituted cathinones which have been popular amongst recreational drug users in the last decade. The chemical was identified as a constituent of head shop powders NRG-1 and NRG-3.

The pharmacological profile of pentylone is that it acts as a reuptake inhibitor of the monoamine neurotransmitters dopamine, noradrenaline and serotonin. It also acts to release serotonin in a weak manner.

The health effects of long term or even short term recreational use of pentylone are unknown. Its toxicological profile has not been fully studied.

The chemical is not for animal or human consumption.

Unverifiable online reports can give us some indication as to the effects of pentylone.

The chemical has been reported as being physically and mentally stimulating. At higher doses users report being unable to remain still. It is reported to accelerate thoughts.

Other reported physical effects of this drug include increased heart rate, sweating, loss of apetite, increased focus, grinding of the teeth and some users report difficulty urinating.

It may induce euphoria.The chemical is also reported to increase the ego of some users, increase motivation, produce a loss of inhibition, stimulate the libido and enhance appreciation for music.

In a similar manner to other drugs of the cathinone class, pentylone may induce states of psychosis and acute paranoia at higher doses or if used for prolonged periods of time.

It is known to be addictive and has been reported to cause users to compulsively re-dose during their “high”.

Negative after effects have been reported including exhaustion of mind and body, depression, anxiety, irritability, loss of motivation and inability to sleep.

It is considered dangerous to mix pentylone with alcohol.

Other names and synonyms for Pentylone :

1-(1,3-Benzodioxol-5-yl)-2-(methylamino)-1-pentanon [German] [ACD/IUPAC Name]
1-(1,3-Benzodioxol-5-yl)-2-(methylamino)-1-pentanone [ACD/IUPAC Name]
1-(1,3-Benzodioxol-5-yl)-2-(méthylamino)-1-pentanone [French] [ACD/IUPAC Name]
1-Pentanone, 1-(1,3-benzodioxol-5-yl)-2-(methylamino)- [ACD/Index Name]
Pentylone [Wiki]
698963-77-8 [RN]