Chemical Data :
Molecular Weight: 220.268 g/mol
Molecular Formula: C12H16N2O2
MDBP is a class of designer drugs in the piperazine family
|Weight||WU + Reship||WU -Reship|
Methylenedioxybenzylpiperazine a novel constituent in ecstasy pills has gained particular attention in the drug market. Valued in the market for forensic endeavors and research trials, MDBP has emerged as a toxicological designer drug belonging to piperazine class with particular relation to benzylpiperazines. Although it has gained forensic renown, it still is subject to potential abuse with the purposes of mere recreation. All chemical procedure meant for generating amphetamines can be attributed to chemical formulation of methylenedioxybenzylpiperazines for the chemistry in their processing is almost homologous.
Benzylpiperazines feature multiple substitutions at aromatic rings which principally act as core substance in their constitution. Substitutions comprise of either methyl group, fluorine atom, methoxy group, bromine substitution or a trifluoromethylation at one of the positions of the aromatic core.
It also acts as father drug of various medically significant drugs as antiparkinsonian drug, piribedil and dilators of both bronchioles and coronaries as medibazine.
It harbors a chemical formulation as depicted by its formula as C12H16N2O2 • 2HCl with molecular weight as 293.2 g/mol for its crystalline form.
Methylenedioxybenzylpiperazine cannot be readily identified from amongst many of its counterpart MDBP chemical owing to inability of the pivotal method, mass spectrometry which is a principal toxicological technique in forensics to delineate the specific MDBP from others. This incapacity of mass spectrometry is attributable to regioisomerism, hence another method for toxicological identification has been recruited for the purpose. Gas chromatography associated with infra red detection methods (GC-IRD) spectrometry is necessary as an identification tool. Furthermore no chemical modifications are required to render the drug identifiable by gas chromatography. Whatsoever, acid hydrolysis, microwave associated acetylation and liquid/liquid extractive methods are essential for identification of unique chemicals within urine specimens.
Pieprazines mimic the psychedelic effects of ecstasy pills via activation of 5-hydroxytyrptamine receptor. Activation corresponds to release of monoamine neurotransmitters in to central nervous system. Therefore dopamine together with norepinephrine incites empathy, luring love and intimacy among the users. Methlenedioxybenzylpiperazine effects are homologous to empathogenic psychoactivation.
Piperazines when used in toxic concentrations can lead to rhabdomyolysis, neurological harm as seizures, hyperthermia and renal dysfunction. Legally the use of these designer drugs as MDBP should be highly controlled to prevent their lethal side effects as seizures can ensue to fatality. Putting ban on the precursor molecule, piperazine, of these illicit designer drugs won’t prove to be a toxicity sparing strategy.