Chemical Data :

IUPAC: 1-(1,3-Benzodioxol-5-yl)-2-(ethylamino)-1-propanone

CAS: 1112937-64-0

ChemSpider: 21106271

Molecular Weight: 221.252

Molecular Formula: C12H15NO3

Ethylone, otherwise known as βk-MDEA, MDEC and 3,4-methylenedioxy-N-ethylcathinone, is  a stimulant and possible “enttactogen” of the substituted cathinone class of drugs.

Ethylone is the β-keto analogue of MDEA. It shares a similar relationship as methylone to MDMA.

It has a short period of use, with ethylone first being sold in 2011. Ethylone has been linked to a number or drug related deaths.

Ethylone has the formal and systematic IUPAC name 1-(1,3-Benzodioxol-5-yl)-2-(ethylamino)-1-propanone. It has a molar mass of 221.2524 grams and empirical formula C12H15NO3.

The substituted cathinones are a class of synthetic compounds that have bear a structural relation to cathinone, a compound found in nature. The basic cathinone compound is a phenethylamine, consisting of a six member aryl ring bound to an amine(NH2) via an ethyl bridge. The beta carbon, beside the aryl ring and two places away from the amine, is bonded to anoxygen to make a ketone. At the alpha carbon there is a methyl substitution. This is the basic backbone. To this various substitutions can be made on to the aryl ring. Further, alkyl substitutions of various lengths are tolerated at the alpha carbon. The nitrogen is typically n-alkylated in most substituted cathinones, or incorporated in to a saturated ring structure. 

Chemically they are closely related to amphetamines. To make an amphetamine in to a cathinone, one need only add a ketone group to the beta carbon of the phenethylamine backbone. The resulting cathinones are often comparatively weaker versions of their amphetamine cousins. The beta ketone derivative of MDMA is methylone – a stimulating compound which apparently produced a similar “loved up” feeling as ecstacy.  The amphetamine MDEA, also known as “eve” is the ethyl analogue of MDMA. It reportedly has similar effects to MDMA as well. The cathinone version of MDEA is ethylone.

Ethylone presumably causes an increase in the concentration of extracellular monoamine neurotransmitters in the brain. In particular, an increase of serotonin in the synapse is thought to produce the empathogenic qualities of these compounds.

The health effects of short term of long term recreational use of ethylone are not known.

It is not fit for human consumption.

Unverifiable online reports give us some indication as to the effects of this compound.

Ethylone reportedly produces feeling of euphoria, stimulation and an increased appreciation for music. Some users report feeling more connected to others and the world around them. It is said to lower inhibitions and soften boundaries allowing people to feel more empathy with others. Furthermore there are reports of ethylone producing a feeling of inner peace and tranquillity.

Negative effects of ethylone are also commonly reported. These include, but are not limited to, nausea, anxiety, dry mouth and states of paranoia. The after effects may leave one feeling mental and physical tired, emotionally drained and depressed and lacking motivation.

As with all stimulants, excessive or prolonged use may lead to psychotic states. This is known as stimulant psychosis. Disturbing auditory and visual hallucinations may manifest as well as a feeling of dread or impending doom.

Other names and synonyms

1-(1,3-Benzodioxol-5-yl)-2-(ethylamino)-1-propanon [German] [ACD/IUPAC Name]
1-(1,3-Benzodioxol-5-yl)-2-(ethylamino)-1-propanone [ACD/IUPAC Name]
1-(1,3-Benzodioxol-5-yl)-2-(éthylamino)-1-propanone [French] [ACD/IUPAC Name]
1-Propanone, 1-(1,3-benzodioxol-5-yl)-2-(ethylamino)- [ACD/Index Name]
Ethylone [Wiki]
1112937-64-0 [RN]