Diethylone crystal

Chemical Data :

IUPAC:3′,4′-Methylenedioxy-N,N-diethylcathinone (hydrochloride) RM


ChemSpider: N/A

Molecular Weight: N/A

Molecular Formula: N/A

Diethylone, also known as 5-BDDE, 3′,4′-Methylenedioxy-N,N-diethylcathinone and N-Ethylethylone, is a stimulant designer drug of the substituted cathinone class.

It has the formal and systematic IUPAC 1-(benzo[d][1,3]dioxol-5-yl)-2-(diethylamino)propan-1-one, monohydrochloride. Diethylone has the empirical chemical formula C14H19NO3 • HCl and a relative molar mass of 285.8 grams. It forms a neat solid at room temperature and pressure.

The chemical structure of diethylone is typical of a substituted cathinone compound. The phenethylamine backbone is substituted at the alpha carbon by a methyl group and the beta carbon has a ketone attached. The nitrogen is N-alkylated with two ethyl groups and the aryl ring has a 3, 4 methylenedioxy substitution reminiscent of MDMA and methylone.

Diethylone presumably exerts its stimulant action by increasing the interstitial concentrations of monoamine neurochemicals in the CNS.

Cathinones, such as diethylone, are also known as beta-keto amphetamines. This multitudinous class of compounds has had a surge in popularity in the last decade.

Synthetic cathinones have a surprisingly long history of use. Methcathinone was first used as an anti-depressant in the USSR in the 1930s. Its medical use would be abandoned, but it would later be used in the 1970s and 1980s in the USSR as a party drug and also as a recreational chemical during the 1990s in the USA. The substituted cathinones came to much wider prominence in the west at the end of the last decade. In particular mephedrone (4MMC) was widely popular in the UK in 2009 and 2010. Its widespread abuse in the UK and Ireland led to the cathinone compounds becoming controlled substances in these countries.

The substituted cathinones all bear a structural relationship to cathinone a compound found in nature. Cathinone is found in the leaves of Catha edulis, a shrub that is native to the Arabian Peninsula and the Horn of Africa. People from these regions have used the leaf of this plant, known as Khat, for over two hundred years. The fresh leaf is chewed to release the psychoactive alkaloids. The primary stimulatory agent cathinone, encourages sociability and talkativeness in users and reduces feelings of tiredness. This plant is now farmed intensively in these regions.

The health effects of long term or short term recreational use of diethylone are not known. There has been no toxicological study in to its effects on humans.

Diethylone is not fit for human or animal consumption.

Unverifiable online reports give us some indication as to the effects of this compound.

It is reported to be a mild stimulant.

Positive reported effects include stimulation, lowered inhibitions, increased appreciation of music, softening of social boundaries, euphoria, enhanced feelings of empathy and enhanced sociability.

Negative effects which have been reported include anxiety, sweating, dehydration, dry mouth, hypertenstion, heart palpations and abnormal heart beat, tachycardia and nausea.

Diethylone may cause paranoia. Like other cathinones if used over prolonged periods of time there is the risk of acute development of acute periods of anxiety, paranoia and psychosis known as stimulant psychosis.

Diethylone is considered to be mildly addictive with a high potential for abuse.