Chemical Data :

IUPAC: 2-Amino-1-(4-bromo-2,5-dimethoxyphenyl)ethan-1-one

CAS: 807631-09-0

ChemSpider: 9463799

Molecular Weight: 310.572 g/mol

Molecular Formula: C10H12BrNO3

Bk-2C-B, also known as beta-keto 2C-B and βk-2C-B, is a psychedelic and stimulant phenethylamine drug compound closely related to the widely known compound 2-CB.

It has the formal and systematic IUPAC name 2-Amino-1-(4-bromo-2,5-dimethoxyphenyl)ethan-1-one.

The phenethylamine compounds are defined as having an aromatic six member bonded to an amino (NH2) via an ethyl bridge. Bk-2C-B has three substitutions on the aromatic ring. Bromine atom is bonded at the para position, along with two methyoxy substitutions at positions 2 and 5 of the ring. In addition to this the ethyl bridge contains a ketone substituted at the beta carbon. This transforms it in to a beta keto analogue of 2-CB in much the same way as a cathinone is a beta keto analogue of an amphetamine.

Bk-2C-B is believed to act as a partial agonist at serotonin receptor 5HT2a. Other compounds that share this pharmacological action include LSD and psilocybin, the primary psychoactive constituent of “magic mushrooms”. Just how this partial agonist action at 5HT2a brings about the psychedelic effects remains unknown.

Bk-2C-B has a short period of human use, only coming to light in 2014. There are no studies in to the effects on health of short term or long term recreational use of Bk-2C-B.

Bk-2C-B is not fit for human or animal consumption.

Unverifiable online reports give us some insight in to the effects of this compound.

It is reported as being significantly more stimulating and of having less psychedelic character than its analogue 2-CB.

Reported physical effects include stimulation, enhancement of touch and wakefulness. Also reported is dilation of pupils and nausea.

Cognitively Bk-2C-B is said to produce a range of psychedelic effects at 80 – 100 mg. These include acceleration of thoughts, enhancement of music, magnification of emotions, distortion of the perception of time, feelings of novelty, enhanced analysis, and reduction in personal bias, immersion in activities, conceptual thinking, looping thoughts, delusions, loss or death of ego, confusion and or disorganisation of thought.

Visual effects are reported as enhancement of colour, enhanced visual acuity and increased pattern recognition. Distortions of the visual field are reported including melting, flowing, breathing and morphing of objects, noticeable visual tracers and after images and changing colours.

Internal hallucinations are also reported including alterations in perspective, sceneries, landscapes, autonomous entities and scenarios with plots.

Auditory effects which have been reported include enhancement of sound, hallucinations and noticeable distortion of sound.

Bk-2C-B is unlikely to be habit forming. It does produce tolerance however. This means if taken two days in a row, effects will be much less pronounced on the second day. This tolerance reduces by half within 7 days and ought to return to normal within one week provided there is no further consumption. Bk-2C-B reportedly has cross tolerance with all other psychedelic compounds meaning that after consumption of Bk-2C-B other psychedelics will have a reduced effect for a period of time and vice versa.

It is perhaps advisable for potential users to have a sober “trip sitter” present to help guide the experience.

Other names and synonyms

Beta-keto 2C-B, Bk-2C-B
2-Amino-1-(4-brom-2,5-dimethoxyphenyl)ethanon [German] [ACD/IUPAC Name]
2-Amino-1-(4-bromo-2,5-dimethoxyphenyl)ethanone [ACD/IUPAC Name]
2-Amino-1-(4-bromo-2,5-diméthoxyphényl)éthanone [French] [ACD/IUPAC Name]
Ethanone, 2-amino-1-(4-bromo-2,5-dimethoxyphenyl)- [ACD/Index Name]