A-PVT Crystal


Chemical Data :

IUPAC: 2-(pyrrolidin-1-yl)-1-(thiophen-2-yl)pentan-1-one

CAS: 1400742-66-6

ChemSpider: 29738196

Molecular Weight: 237.4 g/mol

Molecular Formula: C13H19NOS

A-PVT Crystal Profile

The chemical is also known as Pyrrolidinopentiothiophenone and α-PVT. It is a synthetic drug of the thiophenyl beta ketone class and an analogue of α-PVP where the phenyl ring is replaced with a thiophene (a sulphur containing five member unsaturated ring moiety).

A-PVT was first identified by a forensic laboratory in Japan. It has been shown to be highly cytotoxic. This means the presence of A-PVT was shown to kill human cells in the laboratory. The chemical is classified as a hazardous chemical substance in Sweden.

The substituted cathinones, from which A-PVT is derived, are a class of stimulants otherwise known as the beta keto amphetamines. They have emerged in the last fifteen years to prominence amongst the range of research chemical “highs”. They are all derived from the plant derived chemical known as cathinone which is a beta keto analogue of amphetamine or “speed”. Cathinone comes from the plant Catha edulis which is a native shrub of the Horn of Africa. The fresh leaves are chewed in a herbal drug preparation known as Khat. Khat has been consumed in the Middle East and north west Africa for over 200 years and its consumption is considered a long standing tradition of many cultures in that region. It is typical used by manual labourers after work, to reduce feelings of tiredness and as a social lubricant that increases talkativeness, energy and sociability. It has reached such popularity that the plant Catha edulis is now farmed intensively as a cash crop.

The substituted cathinones are synthetic modifications of the cathinone compound which have been sold online in the last decade in a much more potent powdered form. One of these, methcathinone, was in fact used as an anti-depressant in the USSR in the 1930s. Later it would be used as a recreational drug in the 1970s and 1980s in the USSR and later in the 1990s in the USA.

The pyyrolidinophenone cathinones emerged as a subset of the substituted cathinones with six new members of this class being discovered by research scientists in Germany at the turn of the century.

The pyyrolidinophenone cathinones take the cathinone structure but include the nitrogen in a five member ring. A-PVP is one example of these. The chemical also includes the five member nitrogen ring of this class of compounds and the beta keto substitution. However the phenyl aromatic ring has been replaced with a sulphur containing ring meaning that A-PVT due to this modification likely no longer can be classified as a cathinone at all.

A-PVT supposedly entered distribution from online vendors in 2012. It is very likely an attempt to produce a chemical that evades drug legislation for substituted cathinones by replacing the phenyl ring with a thiophene ring producing a compound of crude similarity that may or may not have positive subjective effects.

The chemical is not fit for human or animal consumption.

Little is known about the safe dosage range and the toxicity profile of A-PVT and the thiophenyl beta ketones.

Some unverifiable online reports claim A-PVT to have similar stimulatory effects to A-PVP but comparatively much weaker. There are some reports of extremely uncomfortable “comedowns” with physiological side effects including highly elevated heart rate and physical tension.

The pyyrolidinophenone cathinones to which APVT bears a structural similarity are known to be highly reinforcing and cause users to spontaneously re-dose. They can cause induced stimulant psychosis at higher doses or if used over extended periods.

A-PVT may also be habit forming.

Other names and synonyms for A-PVT:

1-Pentanone, 2-(1-pyrrolidinyl)-1-(2-thienyl)- [ACD/Index Name]
2-(1-Pyrrolidinyl)-1-(2-thienyl)-1-pentanon [German] [ACD/IUPAC Name]
2-(1-Pyrrolidinyl)-1-(2-thienyl)-1-pentanone [ACD/IUPAC Name]
2-(1-Pyrrolidinyl)-1-(2-thiényl)-1-pentanone [French] [ACD/IUPAC Name]
1400742-66-6 [RN]