A-PVP Crystal


Chemical Data

IUPAC: (RS)-1-Phenyl-2-(1-pyrrolidinyl)-1-pentanone

CAS: 14530-33-7

ChemSpider: 9324063

Molecular Mass: 231.333 g/mol

Molecular Formula: C15H21NO

A-PVP Crystal Profile

The chemical also goes by the names α-PVP, Alpha-PVP, Pyrrolidinopentiophenone and  flakka. It is a stimulant drug of the cathinone class. Within the substituted cathinones it can be further classified in to a pyrolaverone sub category. A-PVP bears a structural similarity to MDPV which is also a cathinone and pyrolaverone.

It has the formal and systematic IUPAC name (RS)-1-Phenyl-2-(1-pyrrolidinyl)-1-pentanone, molar mass of 231.333 grams and empirical formula C15H21NO.

Structurally the chemical may be described as a 1-pentanone sunstituted with a phenyl group at position one and a pyrrolidinyl moiety at position 2.

The pharmacology of the chemical is not known. There is some conjecture that owing to a similarity in the profile of effects and structural similarities that A-PVP acts similarly to MDPV which is an NDRI (noradrenaline dopamine reuptake inhibitor).

It remains untested in humans. There are no studies in to the health effects of long term or short term recreational use of A-PVP.

It is not fit for human or animal consumption.

Unverifiable online reports have brought to light some of the subjective experiences of use of A-PVP.

Reports describe the body high as a moderate to extreme tingling. This sensation is said to envelope the entire body. At larger doses this sensation has been described as overwhelming. The so called “body high” rises throughout the onset of the experience to a limit at the peak of the experience.

A-PVP is described online as causing significant physical stimulation. Users report the stimulation has a forceful nature and as such as larger doses it is actually difficult to remain still. Involuntary shaking and vibration of the body may arise as well as tight clenching of the jaw and unsteady hands and lack of motor co-ordination.

Some users have reported vibration in their visual field caused by spontaneous wiggling of the eyes.

Dehydration is a common adverse effect. Additionally it is reported that urination may be difficult during the experience. Vasoconstriction is reported as being on par with methamphetamine.

Other physical effects reported include sweating and elevated heart rate.

Cognitive effects that have been reported are an extreme mental stimulation and powerful sense of euphoria. The quality of the euphoria is said to be similar to that of amphetamine. Thoughts are accelerated and some report an increased appreciation in music.

The after effects which have been reported include feelings of mental tiredness, anxiety, low motivation, depression, irritability and a trouble sleeping.

A-PVP like other stimulants has a high potential for abuse. It is considered moderately addictive and users may develop a psychological addiction to it. Members of the cathinone class are recognised to be reinforcing agents.  After repeated and long term use cessation may bring about withdrawal effects and cravings.

Tolerance to the effects of A-PVP is reported with repeated use meaning higher doses are required for qualitatively similar effects. Tolerance is said to return to baseline levels after two weeks of abstinence.

A-PVP may induce stimulant psychosis if used excessively or in high doses. It should not be used in combination with alcohol.

Other names and synonyms of A-PVP :

14530-33-7 [RN]
1-Pentanone, 1-phenyl-2-(1-pyrrolidinyl)- [ACD/Index Name]
1-Phenyl-2-(1-pyrrolidinyl)-1-pentanon [German] [ACD/IUPAC Name]
1-Phenyl-2-(1-pyrrolidinyl)-1-pentanone [ACD/IUPAC Name]
1-Phényl-2-(1-pyrrolidinyl)-1-pentanone [French] [ACD/IUPAC Name]
α-Pyrrolidinopentiophenone [Wiki]
MFCD24386810 [MDL number]