Chemical Data :

IUPAC: 1-(4-methoxyphenyl)-2-(1-pyrrolidinyl)-1-pentanone

CAS: 5537-19-9

ChemSpider: N/A

Molecular Weight: 261.17

Molecular Formula: C16H23NO2

4-MeO-PVP Profile

The chemical is also known as 4’-methoxy-2-(1-pyrrolidinyl)-Valerophenone, 4-methoxy-α-Pyrrolidinovalerophenone and 4-MeO-α-PVP. It goes by the formal and systematic IUPAC name 1-(4-methoxyphenyl)-2-(1-pyrrolidinyl)-1-pentanone.

The chemical has a relative molar mass of 297.8 grams and empirical formula C16H23NO2. It forms a crystalline solid at room temperature.

The chemical is a member of the pyrrolidinophenone class of substituted cathinones along with α-PVP, 4F-PVP and MDPV.

The chemical is an analogue of α-PVP. They share the same structure but 4-Meo-PVP has a para methoxy substitution on the phenyl ring.

The health impact of short term or long term recreational use of 4-Meo-PVP is not known. Its pharmacological and toxicological profile in humans is unknown.

4-Meo-PVP is not for human or animal consumption.

Unverifiable online reports shed some light on the effects of 4-Meo-PVP.

It is reported that 4-Meo-PVP provides a subtle but acceptable high that is qualitatively similar to other pyyrolidinophenone cathinones like MDPV and α-PVP.

There are a range of physical effects that have been reported. The “body high” is described as a euphoric sensation that envelops the entire body. This phenomenon is apt to become overwhelming at high doses. The tingling sensation produced is said to rise with steady persistence from the onset levelling off at the peak of the experience. Sense of touch is said to be enhanced.

Like other pyyrolidinophenone cathinones, the research chemical is reported to be extremely physically stimulating in nature. Users report feeling energetic and the state produced is conducive to dancing. The stimulation is described as feeling forceful in nature. At high doses in fact it is said that one is unable to remain still and the physical stimulation may manifest as shaking legs, trembling of the hands and involuntary movement of the eyes and mouth. A lack of general motor control is reported at high doses.

Nystagmus, or vibration of the eyes, is a reported feature of the “high”. Other side effects include sweating, dehydration, problems urinating, increased heart rate, markedly reduced appetite, loss of some degree of visual acuity and grinding of the teeth.

Cognitively 4-Meo-PVP is reported as producing a mental state of euphoria. Thoughts are reported to be accelerated and some users report a greater degree of emersion in the task at hand. Also reported are an increase in libido analogous to the effect of MDPV, enhanced motivation, enlargement of the ego and an increased appreciation for music.

4-Meo-PVP has been reported as causing a compulsion to re-dose in some users and a craving for more after the peak experience of the “high”.

The after effects of 4-Meo-PVP are reported as being uncomfortable and negative. Specifically this includes a difficulty sleeping, feelings of depression and irritability, slower thoughts, tiredness of mind and body and anxiety.

The pyyrolidinophenone cathinone stimulants are associated with producing psychotic states after heavy prolonged usage or at high doses. They may induce states of acute paranoia and terror.

4-Meo-PVP is considered moderately addictive and has a high potential for abuse. After continual use some users report withdrawal effects and cravings. It also seems to produce tolerance.

Other names and synonyms for 4-Meo-PVP:

  • 4′-Methoxy-α-Pyrrolidinopentiophenone
  • 4-MeO-α-PVP