Chemical Data

ChemSpider : 24583389

IUPAC: 2-(4-chloro-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine

CAS: 1227608-02-7

Molecular Mass: 1227608-02-7

Molecular Formula: C18H22ClNO3

25C-NBOMe (also known as NBOMe-2C-C and 2C-C-NBOMe) psychedelic drug compound and derivative of the phenethylamine psychedelic 2C-C.

25-C-NBOMe was discovered in2001 at the Free University of Berlin by chemist Ralf Heim.

It has the formal and systematic IUPAC name 2-(4-chloro-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine, an empirical formula of C18H22ClNO3 and a relative molar mass of 335.83 grams.

25C-NBOMe is a partial agoinist at human serotonin receptor 5HT2a. Other drugs with partial agonist activity at 5HT2a include LSD, mescaline and pslocibin. It is unclear how this interaction produces the psychedelic effect.

25C-NBOMe is sixteen times more potent than its derivative 2C-C. This means that even at high doses it can be dissolved and put in liquid form on to blotter paper. Members of the NBOMe series of psychedelics have been mistaken for LSD in the past. However in comparison to LSD, 25C-NBOMe only has one third the potency.

This chemical is not orally active. Drugs of the NBOMe class are absorbed in to the body by the sublingual route. The substance is reportedly placed below the tongue and not swallowed for some time. A harsh and metallic taste is reported as well as a numbing effect. This is one way users are able to distinguish it from LSD which is tasteless.

25-C-NBOMe is not for human or animal consumption. The following information is from online reports and is not verifiable.

Like other members of the NBOMe series the psychedelic effects of NBOMe are long lasting. The total duration of the “trip” is reported as being 8 – 10 hours. It is a faster “come up” than LSD with effects taking hold within the first 15 minutes. The “come up” is quite long lasting for up to 90 minutes. Peak effects typically last for between 4-6 hours with an offset period of between 1 -4 hours.

Threshold doses are reported in the range of 50-100 µg. Common doses are reported as 300 -700 µg. It is worth noting that unlike LSD, 25C-NBOMe is highly toxic at heavy doses and overdose can be fatal.

25C-NBOMe is reported as producing strong visual hallucinations including changes in colour. It can induce euphoria, stimulation and mood lift. Appreciation and awareness of music is enhanced. Some users report feelings of love and empathy and life changing spiritual experiences. Like other psychedelics 25C-NBOMe causes the user to undergo a change in their state of consciousness. It may alter subjective perception of time.

Some mild side effects which are reported include unusual body sensations, pupil dilation, jaw clenching, increased heart rate, dissociation and yawning.

Some negative reported effects are of looping thoughts, loss of control of thoughts, paranoia, fear and panic. It may induce states of acute confusion and users may find it difficult to focus. Vasoconstriction, irritation of the throat and other mucus membranes, nausea and vomiting are reported.

It has been strongly suggested that 25C-NBOMe is not insufflated (snorted) due to its extreme potency. This administration method has been linked to a number of fatal overdoses. 25C-NBOMe is not reported as being addictive or habit forming.

Other names and synonyms of 25C-NBOMe

2-(4-Chloro-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine [ACD/IUPAC Name]
2-(4-Chlor-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamin [German] [ACD/IUPAC Name]
2-(4-Chloro-2,5-diméthoxyphényl)-N-(2-méthoxybenzyl)éthanamine [French] [ACD/IUPAC Name]
2C-C-NBOMe [Wiki]
Benzeneethanamine, 4-chloro-2,5-dimethoxy-N-[(2-methoxyphenyl)methyl]- [ACD/Index Name]
1227608-02-7 [RN]
MFCD16659701 [MDL number]